GHK-CU

What is GHK-Cu?

GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper) is a naturally occurring tripeptide originally isolated from human plasma. It forms a stable complex with copper ions, which dramatically increases its biological activity and tissue affinity. First characterized in the 1970s, GHK-Cu has become one of the most studied copper-binding peptides in preclinical research.

Research Context

Investigators have documented GHK-Cu's capacity to upregulate collagen, elastin, and glycosaminoglycan synthesis in tissue culture models. Research has also demonstrated effects on angiogenesis and nerve regeneration, with the compound shown to activate multiple growth factors including VEGF, FGF, and IGF-1 in vitro. Genomic studies suggest GHK-Cu modulates over 4,000 human genes — primarily those involved in tissue remodeling and anti-inflammatory cascades.

Research Applications

• Collagen and extracellular matrix synthesis studies
• Wound healing and tissue regeneration research
• Anti-inflammatory pathway investigation
• Angiogenesis and vascularization models
• Neuroprotection research

For research use only. Not for human or animal consumption.

This compound's precise mechanism continues to be characterized through ongoing preclinical research. Investigators have proposed interactions with growth factor signaling pathways, receptor modulation, and cellular repair cascades. Consult current peer-reviewed literature for the most up-to-date mechanistic hypotheses.

Store lyophilized powder at −20°C for up to 24 months. Once reconstituted with bacteriostatic water, store at 4°C and use within 28 days. Protect from light, moisture, and repeated freeze-thaw cycles. Handle in a clean laboratory environment with appropriate PPE. For research use only — not for human or animal administration.

Use our Peptide Reconstitution Calculator to determine the exact volume of bacteriostatic water to add. Allow the solvent to run down the inside of the vial slowly — do not inject directly onto the lyophilized cake. Swirl gently; do not shake. The solution should appear clear to slightly opalescent.

Orders ship in discreet, unmarked packaging with no reference to Aeternum Labs on the exterior. All shipments include full tracking and are insured against loss or damage. Most orders are dispatched within 1–2 business days. Cold-chain packaging is included where required to maintain compound integrity during transit.