Melanotan 2 (MT-2)

What is Melanotan II?

Melanotan II is a cyclic, shortened analogue of alpha-melanocyte-stimulating hormone containing 7 amino acids in a cyclic ring structure. The cyclic configuration increases metabolic stability relative to linear analogues and produces broader receptor engagement across MC1R, MC3R, MC4R, and MC5R subtypes.

Research Context

Melanotan II has generated substantial preclinical interest across multiple biological domains. MC1R activation drives eumelanin synthesis in melanocyte cultures. MC4R activity has been linked to appetite suppression and energy expenditure in rodent feeding studies. MC4R and MC3R pathways have also been associated with central and peripheral effects on sexual arousal behavior in animal models — a finding that has driven ongoing receptor subtype characterization research. Its broad receptor profile makes it a valuable tool compound for melanocortin pathway dissection.

Research Applications

• Melanocortin receptor pharmacology and subtype selectivity
• Melanogenesis and pigmentation models
• Energy homeostasis and appetite regulation research
• Reward circuitry and behavioral neuroscience
• Sexual function mechanism research

For research use only. Not for human or animal consumption.

This compound's precise mechanism continues to be characterized through ongoing preclinical research. Investigators have proposed interactions with growth factor signaling pathways, receptor modulation, and cellular repair cascades. Consult current peer-reviewed literature for the most up-to-date mechanistic hypotheses.

Store lyophilized powder at −20°C for up to 24 months. Once reconstituted with bacteriostatic water, store at 4°C and use within 28 days. Protect from light, moisture, and repeated freeze-thaw cycles. Handle in a clean laboratory environment with appropriate PPE. For research use only — not for human or animal administration.

Use our Peptide Reconstitution Calculator to determine the exact volume of bacteriostatic water to add. Allow the solvent to run down the inside of the vial slowly — do not inject directly onto the lyophilized cake. Swirl gently; do not shake. The solution should appear clear to slightly opalescent.

Orders ship in discreet, unmarked packaging with no reference to Aeternum Labs on the exterior. All shipments include full tracking and are insured against loss or damage. Most orders are dispatched within 1–2 business days. Cold-chain packaging is included where required to maintain compound integrity during transit.